Design Buzz - Tion, and additional tumor initiating pathways promote mammary carcinogenesis. We have http://design-buzz.com/story.php?title=tion-and-additional-tumor-initiating-pathways-promote-mammary-carcinogenesis-we-have-1321 Tion, and additional tumor initiating pathways promote mammary carcinogenesis. We have previously shown that activated ERK1/2 levels and the migratory action of TERT-siSFRP1 cells are drastically reduced in response to TGF-R inhibition which is consistent with work described by Imamichi et al. showing that TGF- signaling mediates the cellular migration of breast cancer cells by ERK1/2 activation [ Thu, 20 Jun 2019 15:20:32 UTC en